Immune recognition

Immune Recognition

The book consists of seven chapters each of which deals with a specific aspect of interferon action and production. The chapters are essentially compilations of research papers presented at the meeting by scientists from different laboratories. Interestingly, they also include the proceedings of the question-answer sessions that followed the presentations. A small general introduction to the to...

Immune Pattern Recognition System

Innate immune recognition.

The innate immune system is a universal and ancient form of host defense against infection. Innate immune recognition relies on a limited number of germline-encoded receptors. These receptors evolved to recognize conserved products of microbial metabolism produced by microbial pathogens, but not by the host. Recognition of these molecular structures allows the immune system to distinguish infec...

Jonathan D . Ashwell Immune Recognition

Sooner or later, most immunologists must deal with the phenomenon of cellular 'activation'. Lymphocytes normally exist in a resting, or quiescent, state. On receipt of some external stimulus, the cells undergo a cascade of 'activation events' culminating in biological function. For T cells, occupancy of the T cell antigen-specific receptor (TCR) by its ligand (the combination of a peptide antig...

Immune Recognition of Fungal Polysaccharides

The incidence of fungal infections has dramatically increased in recent years, in large part due to increased use of immunosuppressive medications, as well as aggressive medical and surgical interventions that compromise natural skin and mucosal barriers. There are relatively few currently licensed antifungal drugs, and rising resistance to these agents has led to interest in the development of...